c-Met is a proto-oncogene responsible for encoding the high-affinity receptor for hepatocyte growth factor (HGF). Hepatocyte growth factor is also known as scatter factor which participates in HGF/c-MET signaling pathway. This pathway plays vital role in mitogenesis and morphogenesis during embryonic development and wound healing. The controlled natural activity of c-Met and HGF is important in mammalian development, tissue maintenance, and repair. Binding of HGF to c-MET receptor induces several biological responses collectively known as invasive growth program. These responses are elicited due to activation of several pathways such as RAS pathway, PI3K pathway, STAT pathway, beta-catenin pathway and Notch pathway. However, dysregulation of the HGF/c-MET signaling pathway has been associated with the progression of cancers through activation of oncogenic pathways, angiogenesis and metastasis.
The major cancers such as breast, colon and non-small-cell lung carcinoma (NSCLC) are being examined for efficacy with c-MET / HGF inhibitors. Several small molecule c-Met kinase inhibitors have demonstrated clinical efficacy in cancer treatment and many clinical trials are underway. However, as the small molecule inhibitors lack specificity or selectivity they can cause toxicity. Therefore, researchers are increasing focus to develop antibody therapeutics against c-Met or HGF.
In 2019, the market size of C-MET / HGF Inhibitors is xx million US$ and it will reach xx million US$ in 2025, growing at a CAGR of xx% from 2019; while in China, the market size is valued at xx million US$ and will increase to xx million US$ in 2025, with a CAGR of xx% during forecast period.
In this report, 2018 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for C-MET / HGF Inhibitors.
This report studies the global market size of C-MET / HGF Inhibitors, especially focuses on the key regions like United States, European Union, China, and other regions (Japan, Korea, India and Southeast Asia).
This study presents the C-MET / HGF Inhibitors sales volume, revenue, market share and growth rate for each key company, and also covers the breakdown data (sales, revenue and market share) by regions, type and applications. history breakdown data from 2014 to 2019, and forecast to 2025.
For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2014 to 2019.
In global market, the following companies are covered:
Abxign
Abbott Laboratories
Amgen
ArQule
Astex Therapeutics
AVEO Pharmaceuticals
Bristol-Myers Squibb(BMS)
Chroma Therapeutics
Daiichi Sankyo
Deciphera Pharmaceuticals
Eisai
Eli Lilly
Exelixis
Genmab
Galaxy Biotech
GlaxoSmithKline(GSK)
Hutchison MediPharma
Johnson & Johnson
Kringle Pharmaceuticals
Merck
Methylgene
Novartis
Pfizer
ProMetic BioTherapeutics
Takeda Pharmaceutical
Market Segment by Product Type
C-Met Biologic Inhibitors
Small Molecule C-Met Inhibitors
HGF Antagonist Antibodies
C-Met Antagonist Antibodies(MetMAb)
HGF Kringle Variant Antagonists
Market Segment by Application
Hospital Pharmacies
Retail Pharmacies
Drug Stores
Online Sales
Key Regions split in this report: breakdown data for each region.
United States
China
European Union
Rest of World (Japan, Korea, India and Southeast Asia)
The study objectives are:
To analyze and research the C-MET / HGF Inhibitors status and future forecast in United States, European Union and China, involving sales, value (revenue), growth rate (CAGR), market share, historical and forecast.
To present the key C-MET / HGF Inhibitors manufacturers, presenting the sales, revenue, market share, and recent development for key players.
To split the breakdown data by regions, type, companies and applications
To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
To identify significant trends, drivers, influence factors in global and regions
To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
In this study, the years considered to estimate the market size of C-MET / HGF Inhibitors are as follows:
History Year: 2014-2018
Base Year: 2018
Estimated Year: 2019
Forecast Year 2019 to 2025
Summary:
Get latest Market Research Reports on C-MET / HGF Inhibitors. Industry analysis & Market Report on C-MET / HGF Inhibitors is a syndicated market report, published as Global (United States, European Union and China) C-MET / HGF Inhibitors Market Research Report 2019-2025. It is complete Research Study and Industry Analysis of C-MET / HGF Inhibitors market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.