According to our (Global Info Research) latest study, the global Isocitrate Dehydrogenase Inhibitors market size was valued at USD million in 2023 and is forecast to a readjusted size of USD million by 2030 with a CAGR of % during review period.
Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.
Specific mutations in the isocitrate dehydrogenase gene IDH1 have been found in several brain tumors including astrocytoma, oligodendroglioma and glioblastoma multiforme, with mutations found in nearly all cases of secondary glioblastomas, which develop from lower-grade gliomas, but rarely in primary high-grade glioblastoma multiforme.Patients whose tumor had an IDH1 mutation had longer survival. Furthermore, mutations of IDH2 and IDH1 were found in up to 20% of cytogenetically normal acute myeloid leukemia (AML).These mutations are known to produce (D)-2-hydroxyglutarate from alpha-ketoglutarate.(D)-2-hydroxyglutarate accumulates to very high concentrations which inhibits the function of enzymes that are dependent on alpha-ketoglutarate.This leads to a hypermethylated state of DNA and histones, which results in different gene expression that can activate oncogenes and inactivate tumor-suppressor genes. Ultimately, this may lead to the types of cancer described above.Isocitrate dehydrogenase inhibition technology can be effectively applied to the cancer market.
The Global Info Research report includes an overview of the development of the Isocitrate Dehydrogenase Inhibitors industry chain, the market status of DH Inhibitor (IDH1 Mutant Medullary Malignant Tumor, IDH2 Mutant Medullary Malignant Tumor), FLT3 Inhibitor (IDH1 Mutant Medullary Malignant Tumor, IDH2 Mutant Medullary Malignant Tumor), and key enterprises in developed and developing market, and analysed the cutting-edge technology, patent, hot applications and market trends of Isocitrate Dehydrogenase Inhibitors.
Regionally, the report analyzes the Isocitrate Dehydrogenase Inhibitors markets in key regions. North America and Europe are experiencing steady growth, driven by government initiatives and increasing consumer awareness. Asia-Pacific, particularly China, leads the global Isocitrate Dehydrogenase Inhibitors market, with robust domestic demand, supportive policies, and a strong manufacturing base.
Key Features:
The report presents comprehensive understanding of the Isocitrate Dehydrogenase Inhibitors market. It provides a holistic view of the industry, as well as detailed insights into individual components and stakeholders. The report analysis market dynamics, trends, challenges, and opportunities within the Isocitrate Dehydrogenase Inhibitors industry.
The report involves analyzing the market at a macro level:
Market Sizing and Segmentation: Report collect data on the overall market size, including the revenue generated, and market share of different by Type (e.g., IDH1 Mutant Medullary Malignant Tumor, IDH2 Mutant Medullary Malignant Tumor).
Industry Analysis: Report analyse the broader industry trends, such as government policies and regulations, technological advancements, consumer preferences, and market dynamics. This analysis helps in understanding the key drivers and challenges influencing the Isocitrate Dehydrogenase Inhibitors market.
Regional Analysis: The report involves examining the Isocitrate Dehydrogenase Inhibitors market at a regional or national level. Report analyses regional factors such as government incentives, infrastructure development, economic conditions, and consumer behaviour to identify variations and opportunities within different markets.
Market Projections: Report covers the gathered data and analysis to make future projections and forecasts for the Isocitrate Dehydrogenase Inhibitors market. This may include estimating market growth rates, predicting market demand, and identifying emerging trends.
The report also involves a more granular approach to Isocitrate Dehydrogenase Inhibitors:
Company Analysis: Report covers individual Isocitrate Dehydrogenase Inhibitors players, suppliers, and other relevant industry players. This analysis includes studying their financial performance, market positioning, product portfolios, partnerships, and strategies.
Consumer Analysis: Report covers data on consumer behaviour, preferences, and attitudes towards Isocitrate Dehydrogenase Inhibitors This may involve surveys, interviews, and analysis of consumer reviews and feedback from different by Application (DH Inhibitor, FLT3 Inhibitor).
Technology Analysis: Report covers specific technologies relevant to Isocitrate Dehydrogenase Inhibitors. It assesses the current state, advancements, and potential future developments in Isocitrate Dehydrogenase Inhibitors areas.
Competitive Landscape: By analyzing individual companies, suppliers, and consumers, the report present insights into the competitive landscape of the Isocitrate Dehydrogenase Inhibitors market. This analysis helps understand market share, competitive advantages, and potential areas for differentiation among industry players.
Market Validation: The report involves validating findings and projections through primary research, such as surveys, interviews, and focus groups.
Market Segmentation
Isocitrate Dehydrogenase Inhibitors market is split by Type and by Application. For the period 2019-2030, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of value.
Market segment by Type
IDH1 Mutant Medullary Malignant Tumor
IDH2 Mutant Medullary Malignant Tumor
Others
Market segment by Application
DH Inhibitor
FLT3 Inhibitor
Hedgehog Pathway Inhibitor
Others
Market segment by players, this report covers
AGIOS
Aslan Pharmaceuticals
Bayer
Beigene
Bristol-Myers Squibb
Celgene
Daiichi Sankyo
Philogen S.p.A.
Tesaro
Tragara/Adastra
Tocagen
Market segment by regions, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, UK, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Australia and Rest of Asia-Pacific)
South America (Brazil, Argentina and Rest of South America)
Middle East & Africa (Turkey, Saudi Arabia, UAE, Rest of Middle East & Africa)
The content of the study subjects, includes a total of 13 chapters:
Chapter 1, to describe Isocitrate Dehydrogenase Inhibitors product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top players of Isocitrate Dehydrogenase Inhibitors, with revenue, gross margin and global market share of Isocitrate Dehydrogenase Inhibitors from 2019 to 2024.
Chapter 3, the Isocitrate Dehydrogenase Inhibitors competitive situation, revenue and global market share of top players are analyzed emphatically by landscape contrast.
Chapter 4 and 5, to segment the market size by Type and application, with consumption value and growth rate by Type, application, from 2019 to 2030.
Chapter 6, 7, 8, 9, and 10, to break the market size data at the country level, with revenue and market share for key countries in the world, from 2019 to 2024.and Isocitrate Dehydrogenase Inhibitors market forecast, by regions, type and application, with consumption value, from 2025 to 2030.
Chapter 11, market dynamics, drivers, restraints, trends and Porters Five Forces analysis.
Chapter 12, the key raw materials and key suppliers, and industry chain of Isocitrate Dehydrogenase Inhibitors.
Chapter 13, to describe Isocitrate Dehydrogenase Inhibitors research findings and conclusion.
Summary:
Get latest Market Research Reports on Isocitrate Dehydrogenase Inhibitors . Industry analysis & Market Report on Isocitrate Dehydrogenase Inhibitors is a syndicated market report, published as Global Isocitrate Dehydrogenase Inhibitors Market 2024 by Company, Regions, Type and Application, Forecast to 2030. It is complete Research Study and Industry Analysis of Isocitrate Dehydrogenase Inhibitors market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.