Immune checkpoints are proteins that play an important role in regulating the immune system. In cancer, the immune checkpoints are activated to suppress the anti-tumor activity of the immune system thereby suppressing the immune response against the cancer cells. The study of these proteins and pathways has led to the development of a number of immune checkpoint inhibitors as therapies against cancer. Initial preclinical studies showed that antibody blockade of the immune checkpoint molecule CTLA-4 resulted in successful anti-tumor immune responses in the murine cancer models. This was then followed by studies targeting the PD-1/PD-L1 pathway. Ipilimumab and Yervoy were the first immune checkpoint inhibitors introduced in the market. With the promising results of Yervoy, several anti-PD-1 and anti-PD-L1 antibodies have been developed. Although there are number of other checkpoints that have been studied, such as LAG-3 and TIM-3, the only approved immune checkpoint inhibitors include CTLA-4, PD-1 and PD-L1.
The global Immune Checkpoint Inhibitors market is valued at xx million US$ in 2018 is expected to reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2019-2025.
This report focuses on Immune Checkpoint Inhibitors volume and value at global level, regional level and company level. From a global perspective, this report represents overall Immune Checkpoint Inhibitors market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.
At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.
The following manufacturers are covered:
Bristol Myer Squibb
AstraZeneca
Merck & Co.
Roche / Genentech
Incyte Corporation
NewLink Genetics
ArGEN-X
Seattle Genetics
Pfizer
MacroGenics
Celldex Therapeutics
CureTech
Immutep
Innate Pharma
Sorrento Therapeutics
GlaxoSmithKline
GITR, Inc
Segment by Regions
North America
Europe
China
Japan
Segment by Type
PD-1/PD-L1
CTLA-4
Segment by Application
Lung Cancer
Colorectal Cancer
Breast Cancer
Prostate Cancer
Melanoma
Blood Cancer
Other
Table of Contents Executive Summary 1 Immune Checkpoint Inhibitors Market Overview 1.1 Product Overview and Scope of Immune Checkpoint Inhibitors 1.2 Immune Checkpoint Inhibitors Segment by Type1.2.1 Global Immune Checkpoint Inhibitors Production Growth Rate Comparison by Type (2014-2025) 1.2.2 PD-1/PD-L1 1.2.3 CTLA-4 1.3 Immune Checkpoint Inhibitors Segment by Application1.3.1 Immune Checkpoint Inhibitors Consumption Comparison by Application (2014-2025) 1.3.2 Lung Cancer 1.3.3 Colorectal Cancer 1.3.4 Breast Cancer 1.3.5 Prostate Cancer 1.3.6 Melanoma 1.3.7 Blood Cancer 1.3.8 Other 1.4 Global Immune Checkpoint Inhibitors Market by Region1.4.1 Global Immune Checkpoint Inhibitors Market Size Region 1.4.2 North America Status and Prospect (2014-2025) 1.4.3 Europe Status and Prospect (2014-2025) 1.4.4 China Status and Prospect (2014-2025) 1.4.5 Japan Status and Prospect (2014-2025) 1.5 Global Immune Checkpoint Inhibitors Market Size1.5.1 Global Immune Checkpoint Inhibitors Revenue (2014-2025) 1.5.2 Global Immune Checkpoint Inhibitors Production (2014-2025) 2 Global Immune Checkpoint Inhibitors Market Competition by Manufacturers 2.1 Global Immune Checkpoint Inhibitors Production Market Share by Manufacturers (2014-2019) 2.2 Global Immune Checkpoint Inhibitors Revenue Share by Manufacturers (2014-2019) 2.3 Global Immune Checkpoint Inhibitors Average Price by Manufacturers (2014-2019) 2.4 Manufacturers Immune Checkpoint Inhibitors Production Sites, Area Served, Product Types 2.5 Immune Checkpoint Inhibitors Market Competitive Situation and Trends2.5.1 Immune Checkpoint Inhibitors Market Concentration Rate 2.5.2 Immune Checkpoint Inhibitors Market Share of Top 3 and Top 5 Manufacturers 2.5.3 Mergers & Acquisitions, Expansion 3 Global Immune Checkpoint Inhibitors Production Market Share by Regions 3.1 Global Immune Checkpoint Inhibitors Production Market Share by Regions 3.2 Global Immune Checkpoint Inhibitors Revenue Market Share by Regions (2014-2019) 3.3 Global Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 3.4 North America Immune Checkpoint Inhibitors Production3.4.1 North America Immune Checkpoint Inhibitors Production Growth Rate (2014-2019) 3.4.2 North America Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 3.5 Europe Immune Checkpoint Inhibitors Production3.5.1 Europe Immune Checkpoint Inhibitors Production Growth Rate (2014-2019) 3.5.2 Europe Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 3.6 China Immune Checkpoint Inhibitors Production (2014-2019)3.6.1 China Immune Checkpoint Inhibitors Production Growth Rate (2014-2019) 3.6.2 China Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 3.7 Japan Immune Checkpoint Inhibitors Production (2014-2019)3.7.1 Japan Immune Checkpoint Inhibitors Production Growth Rate (2014-2019) 3.7.2 Japan Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 4 Global Immune Checkpoint Inhibitors Consumption by Regions 4.1 Global Immune Checkpoint Inhibitors Consumption by Regions 4.2 North America Immune Checkpoint Inhibitors Consumption (2014-2019) 4.3 Europe Immune Checkpoint Inhibitors Consumption (2014-2019) 4.4 China Immune Checkpoint Inhibitors Consumption (2014-2019) 4.5 Japan Immune Checkpoint Inhibitors Consumption (2014-2019) 5 Global Immune Checkpoint Inhibitors Production, Revenue, Price Trend by Type 5.1 Global Immune Checkpoint Inhibitors Production Market Share by Type (2014-2019) 5.2 Global Immune Checkpoint Inhibitors Revenue Market Share by Type (2014-2019) 5.3 Global Immune Checkpoint Inhibitors Price by Type (2014-2019) 5.4 Global Immune Checkpoint Inhibitors Production Growth by Type (2014-2019) 6 Global Immune Checkpoint Inhibitors Market Analysis by Applications 6.1 Global Immune Checkpoint Inhibitors Consumption Market Share by Application (2014-2019) 6.2 Global Immune Checkpoint Inhibitors Consumption Growth Rate by Application (2014-2019) 7 Company Profiles and Key Figures in Immune Checkpoint Inhibitors Business 7.1 Bristol Myer Squibb7.1.1 Bristol Myer Squibb Immune Checkpoint Inhibitors Production Sites and Area Served 7.1.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.1.3 Bristol Myer Squibb Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.1.4 Main Business and Markets Served 7.2 AstraZeneca7.2.1 AstraZeneca Immune Checkpoint Inhibitors Production Sites and Area Served 7.2.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.2.3 AstraZeneca Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.2.4 Main Business and Markets Served 7.3 Merck & Co.7.3.1 Merck & Co. Immune Checkpoint Inhibitors Production Sites and Area Served 7.3.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.3.3 Merck & Co. Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.3.4 Main Business and Markets Served 7.4 Roche / Genentech7.4.1 Roche / Genentech Immune Checkpoint Inhibitors Production Sites and Area Served 7.4.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.4.3 Roche / Genentech Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.4.4 Main Business and Markets Served 7.5 Incyte Corporation7.5.1 Incyte Corporation Immune Checkpoint Inhibitors Production Sites and Area Served 7.5.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.5.3 Incyte Corporation Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.5.4 Main Business and Markets Served 7.6 NewLink Genetics7.6.1 NewLink Genetics Immune Checkpoint Inhibitors Production Sites and Area Served 7.6.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.6.3 NewLink Genetics Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.6.4 Main Business and Markets Served 7.7 ArGEN-X7.7.1 ArGEN-X Immune Checkpoint Inhibitors Production Sites and Area Served 7.7.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.7.3 ArGEN-X Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.7.4 Main Business and Markets Served 7.8 Seattle Genetics7.8.1 Seattle Genetics Immune Checkpoint Inhibitors Production Sites and Area Served 7.8.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.8.3 Seattle Genetics Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.8.4 Main Business and Markets Served 7.9 Pfizer7.9.1 Pfizer Immune Checkpoint Inhibitors Production Sites and Area Served 7.9.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.9.3 Pfizer Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.9.4 Main Business and Markets Served 7.10 MacroGenics7.10.1 MacroGenics Immune Checkpoint Inhibitors Production Sites and Area Served 7.10.2 Immune Checkpoint Inhibitors Product Introduction, Application and Specification 7.10.3 MacroGenics Immune Checkpoint Inhibitors Production, Revenue, Price and Gross Margin (2014-2019) 7.10.4 Main Business and Markets Served 7.11 Celldex Therapeutics 7.12 CureTech 7.13 Immutep 7.14 Innate Pharma 7.15 Sorrento Therapeutics 7.16 GlaxoSmithKline 7.17 GITR, Inc 8 Immune Checkpoint Inhibitors Manufacturing Cost Analysis 8.1 Immune Checkpoint Inhibitors Key Raw Materials Analysis8.1.1 Key Raw Materials 8.1.2 Price Trend of Key Raw Materials 8.1.3 Key Suppliers of Raw Materials 8.2 Proportion of Manufacturing Cost Structure 8.3 Manufacturing Process Analysis of Immune Checkpoint Inhibitors 8.4 Immune Checkpoint Inhibitors Industrial Chain Analysis 9 Marketing Channel, Distributors and Customers 9.1 Marketing Channel9.1.1 Direct Marketing 9.1.2 Indirect Marketing 9.2 Immune Checkpoint Inhibitors Distributors List 9.3 Immune Checkpoint Inhibitors Customers 10 Market Dynamics 10.1 Market Trends 10.2 Opportunities 10.3 Market Drivers 10.4 Challenges 10.5 Influence Factors 11 Global Immune Checkpoint Inhibitors Market Forecast 11.1 Global Immune Checkpoint Inhibitors Production, Revenue Forecast11.1.1 Global Immune Checkpoint Inhibitors Production Growth Rate Forecast (2019-2025) 11.1.2 Global Immune Checkpoint Inhibitors Revenue and Growth Rate Forecast (2019-2025) 11.1.3 Global Immune Checkpoint Inhibitors Price and Trend Forecast (2019-2025) 11.2 Global Immune Checkpoint Inhibitors Production Forecast by Regions (2019-2025)11.2.1 North America Immune Checkpoint Inhibitors Production, Revenue Forecast (2019-2025) 11.2.2 Europe Immune Checkpoint Inhibitors Production, Revenue Forecast (2019-2025) 11.2.3 China Immune Checkpoint Inhibitors Production, Revenue Forecast (2019-2025) 11.2.4 Japan Immune Checkpoint Inhibitors Production, Revenue Forecast (2019-2025) 11.3 Global Immune Checkpoint Inhibitors Consumption Forecast by Regions (2019-2025)11.3.1 North America Immune Checkpoint Inhibitors Consumption Forecast (2019-2025) 11.3.2 Europe Immune Checkpoint Inhibitors Consumption Forecast (2019-2025) 11.3.3 China Immune Checkpoint Inhibitors Consumption Forecast (2019-2025) 11.3.4 Japan Immune Checkpoint Inhibitors Consumption Forecast (2019-2025) 11.4 Global Immune Checkpoint Inhibitors Production, Revenue and Price Forecast by Type (2019-2025) 11.5 Global Immune Checkpoint Inhibitors Consumption Forecast by Application (2019-2025) 12 Research Findings and Conclusion 13 Methodology and Data Source 13.1 Methodology/Research Approach13.1.1 Research Programs/Design 13.1.2 Market Size Estimation 13.1.3 Market Breakdown and Data Triangulation 13.2 Data Source13.2.1 Secondary Sources 13.2.2 Primary Sources 13.3 Author List
Summary: Get latest Market Research Reports on Immune Checkpoint Inhibitors . Industry analysis & Market Report on Immune Checkpoint Inhibitors is a syndicated market report, published as Global Immune Checkpoint Inhibitors Market Research Report 2019. It is complete Research Study and Industry Analysis of Immune Checkpoint Inhibitors market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.
Last updated on 13 March, 2019