Severe deficiency of alpha-1 antitrypsin (AAT) can cause early-onset emphysema and several liver diseases, including cirrhosis, neonatal hepatitis and hepatocellular carcinoma.
The discovery of the structure and function of the AAT protein and the subsequent isolation and purification thereof have made possible alternative therapies aimed at preventing the progression of related pulmonary diseases (so-called "additional therapies"). The isolation of this gene and the advancement of gene therapy have further increased the possibility of specific treatment. Most specific treatments for AAT deficiency aim to increase plasma AAT levels (and thus elevated AAT concentrations in the interstitial lung) above the protection threshold. Other experimental therapeutic approaches attempt to interfere with the production of abnormal AAT proteins or to inhibit the polymerization of abnormal AAT proteins and to promote the secretion of AAT from hepatocytes. For patients with end-stage lung disease or liver disease, organ transplantation is another treatment option.
Currently, the most direct and effective way to increase AAT levels in plasma and interstitial lung is by intravenous infusion of pooled alpha-1 antitrypsin (pAAT).
The global Alpha 1 Antitrypsin Deficiency Treatment market is valued at 1190 million US$ in 2018 is expected to reach 2560 million US$ by the end of 2025, growing at a CAGR of 10.1% during 2019-2025.
This report focuses on Alpha 1 Antitrypsin Deficiency Treatment volume and value at global level, regional level and company level. From a global perspective, this report represents overall Alpha 1 Antitrypsin Deficiency Treatment market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.
At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.
The following manufacturers are covered:
Pfizer
Baxter
AstraZeneca
Grifols
Teva Pharmaceutical Industries
Boehringer Ingelheim
Kamada Ltd
GlaxoSmithKline
CSL Behring
Shire
LFB Biomedicaments
Abeona Therapeutics
Biogen
Applied Genetic Technologies
Baxalta
Arrowhead Research Corporation
ProBioGen
Chiesi Pharmaceuticals
Curaxys
ProMetic Life Sciences
Segment by Regions
North America
Europe
China
Japan
Segment by Type
Augmentation Therapy
Bronchodilators
Corticosteroids
Oxygen Therapy
Segment by Application
Hospitals
Specialty Clinics
Pharmacies
Table of Contents Executive Summary 1 Alpha 1 Antitrypsin Deficiency Treatment Market Overview 1.1 Product Overview and Scope of Alpha 1 Antitrypsin Deficiency Treatment 1.2 Alpha 1 Antitrypsin Deficiency Treatment Segment by Type1.2.1 Global Alpha 1 Antitrypsin Deficiency Treatment Production Growth Rate Comparison by Type (2014-2025) 1.2.2 Augmentation Therapy 1.2.3 Bronchodilators 1.2.4 Corticosteroids 1.2.5 Oxygen Therapy 1.3 Alpha 1 Antitrypsin Deficiency Treatment Segment by Application1.3.1 Alpha 1 Antitrypsin Deficiency Treatment Consumption Comparison by Application (2014-2025) 1.3.2 Hospitals 1.3.3 Specialty Clinics 1.3.4 Pharmacies 1.4 Global Alpha 1 Antitrypsin Deficiency Treatment Market by Region1.4.1 Global Alpha 1 Antitrypsin Deficiency Treatment Market Size Region 1.4.2 North America Status and Prospect (2014-2025) 1.4.3 Europe Status and Prospect (2014-2025) 1.4.4 China Status and Prospect (2014-2025) 1.4.5 Japan Status and Prospect (2014-2025) 1.5 Global Alpha 1 Antitrypsin Deficiency Treatment Market Size1.5.1 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue (2014-2025) 1.5.2 Global Alpha 1 Antitrypsin Deficiency Treatment Production (2014-2025) 2 Global Alpha 1 Antitrypsin Deficiency Treatment Market Competition by Manufacturers 2.1 Global Alpha 1 Antitrypsin Deficiency Treatment Production Market Share by Manufacturers (2014-2019) 2.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue Share by Manufacturers (2014-2019) 2.3 Global Alpha 1 Antitrypsin Deficiency Treatment Average Price by Manufacturers (2014-2019) 2.4 Manufacturers Alpha 1 Antitrypsin Deficiency Treatment Production Sites, Area Served, Product Types 2.5 Alpha 1 Antitrypsin Deficiency Treatment Market Competitive Situation and Trends2.5.1 Alpha 1 Antitrypsin Deficiency Treatment Market Concentration Rate 2.5.2 Alpha 1 Antitrypsin Deficiency Treatment Market Share of Top 3 and Top 5 Manufacturers 2.5.3 Mergers & Acquisitions, Expansion 3 Global Alpha 1 Antitrypsin Deficiency Treatment Production Market Share by Regions 3.1 Global Alpha 1 Antitrypsin Deficiency Treatment Production Market Share by Regions 3.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue Market Share by Regions (2014-2019) 3.3 Global Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 3.4 North America Alpha 1 Antitrypsin Deficiency Treatment Production3.4.1 North America Alpha 1 Antitrypsin Deficiency Treatment Production Growth Rate (2014-2019) 3.4.2 North America Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 3.5 Europe Alpha 1 Antitrypsin Deficiency Treatment Production3.5.1 Europe Alpha 1 Antitrypsin Deficiency Treatment Production Growth Rate (2014-2019) 3.5.2 Europe Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 3.6 China Alpha 1 Antitrypsin Deficiency Treatment Production (2014-2019)3.6.1 China Alpha 1 Antitrypsin Deficiency Treatment Production Growth Rate (2014-2019) 3.6.2 China Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 3.7 Japan Alpha 1 Antitrypsin Deficiency Treatment Production (2014-2019)3.7.1 Japan Alpha 1 Antitrypsin Deficiency Treatment Production Growth Rate (2014-2019) 3.7.2 Japan Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 4 Global Alpha 1 Antitrypsin Deficiency Treatment Consumption by Regions 4.1 Global Alpha 1 Antitrypsin Deficiency Treatment Consumption by Regions 4.2 North America Alpha 1 Antitrypsin Deficiency Treatment Consumption (2014-2019) 4.3 Europe Alpha 1 Antitrypsin Deficiency Treatment Consumption (2014-2019) 4.4 China Alpha 1 Antitrypsin Deficiency Treatment Consumption (2014-2019) 4.5 Japan Alpha 1 Antitrypsin Deficiency Treatment Consumption (2014-2019) 5 Global Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price Trend by Type 5.1 Global Alpha 1 Antitrypsin Deficiency Treatment Production Market Share by Type (2014-2019) 5.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue Market Share by Type (2014-2019) 5.3 Global Alpha 1 Antitrypsin Deficiency Treatment Price by Type (2014-2019) 5.4 Global Alpha 1 Antitrypsin Deficiency Treatment Production Growth by Type (2014-2019) 6 Global Alpha 1 Antitrypsin Deficiency Treatment Market Analysis by Applications 6.1 Global Alpha 1 Antitrypsin Deficiency Treatment Consumption Market Share by Application (2014-2019) 6.2 Global Alpha 1 Antitrypsin Deficiency Treatment Consumption Growth Rate by Application (2014-2019) 7 Company Profiles and Key Figures in Alpha 1 Antitrypsin Deficiency Treatment Business 7.1 Pfizer7.1.1 Pfizer Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.1.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.1.3 Pfizer Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.1.4 Main Business and Markets Served 7.2 Baxter7.2.1 Baxter Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.2.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.2.3 Baxter Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.2.4 Main Business and Markets Served 7.3 AstraZeneca7.3.1 AstraZeneca Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.3.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.3.3 AstraZeneca Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.3.4 Main Business and Markets Served 7.4 Grifols7.4.1 Grifols Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.4.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.4.3 Grifols Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.4.4 Main Business and Markets Served 7.5 Teva Pharmaceutical Industries7.5.1 Teva Pharmaceutical Industries Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.5.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.5.3 Teva Pharmaceutical Industries Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.5.4 Main Business and Markets Served 7.6 Boehringer Ingelheim7.6.1 Boehringer Ingelheim Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.6.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.6.3 Boehringer Ingelheim Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.6.4 Main Business and Markets Served 7.7 Kamada Ltd7.7.1 Kamada Ltd Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.7.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.7.3 Kamada Ltd Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.7.4 Main Business and Markets Served 7.8 GlaxoSmithKline7.8.1 GlaxoSmithKline Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.8.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.8.3 GlaxoSmithKline Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.8.4 Main Business and Markets Served 7.9 CSL Behring7.9.1 CSL Behring Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.9.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.9.3 CSL Behring Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.9.4 Main Business and Markets Served 7.10 Shire7.10.1 Shire Alpha 1 Antitrypsin Deficiency Treatment Production Sites and Area Served 7.10.2 Alpha 1 Antitrypsin Deficiency Treatment Product Introduction, Application and Specification 7.10.3 Shire Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue, Price and Gross Margin (2014-2019) 7.10.4 Main Business and Markets Served 7.11 LFB Biomedicaments 7.12 Abeona Therapeutics 7.13 Biogen 7.14 Applied Genetic Technologies 7.15 Baxalta 7.16 Arrowhead Research Corporation 7.17 ProBioGen 7.18 Chiesi Pharmaceuticals 7.19 Curaxys 7.20 ProMetic Life Sciences 8 Alpha 1 Antitrypsin Deficiency Treatment Manufacturing Cost Analysis 8.1 Alpha 1 Antitrypsin Deficiency Treatment Key Raw Materials Analysis8.1.1 Key Raw Materials 8.1.2 Price Trend of Key Raw Materials 8.1.3 Key Suppliers of Raw Materials 8.2 Proportion of Manufacturing Cost Structure 8.3 Manufacturing Process Analysis of Alpha 1 Antitrypsin Deficiency Treatment 8.4 Alpha 1 Antitrypsin Deficiency Treatment Industrial Chain Analysis 9 Marketing Channel, Distributors and Customers 9.1 Marketing Channel9.1.1 Direct Marketing 9.1.2 Indirect Marketing 9.2 Alpha 1 Antitrypsin Deficiency Treatment Distributors List 9.3 Alpha 1 Antitrypsin Deficiency Treatment Customers 10 Market Dynamics 10.1 Market Trends 10.2 Opportunities 10.3 Market Drivers 10.4 Challenges 10.5 Influence Factors 11 Global Alpha 1 Antitrypsin Deficiency Treatment Market Forecast 11.1 Global Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue Forecast11.1.1 Global Alpha 1 Antitrypsin Deficiency Treatment Production Growth Rate Forecast (2019-2025) 11.1.2 Global Alpha 1 Antitrypsin Deficiency Treatment Revenue and Growth Rate Forecast (2019-2025) 11.1.3 Global Alpha 1 Antitrypsin Deficiency Treatment Price and Trend Forecast (2019-2025) 11.2 Global Alpha 1 Antitrypsin Deficiency Treatment Production Forecast by Regions (2019-2025)11.2.1 North America Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue Forecast (2019-2025) 11.2.2 Europe Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue Forecast (2019-2025) 11.2.3 China Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue Forecast (2019-2025) 11.2.4 Japan Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue Forecast (2019-2025) 11.3 Global Alpha 1 Antitrypsin Deficiency Treatment Consumption Forecast by Regions (2019-2025)11.3.1 North America Alpha 1 Antitrypsin Deficiency Treatment Consumption Forecast (2019-2025) 11.3.2 Europe Alpha 1 Antitrypsin Deficiency Treatment Consumption Forecast (2019-2025) 11.3.3 China Alpha 1 Antitrypsin Deficiency Treatment Consumption Forecast (2019-2025) 11.3.4 Japan Alpha 1 Antitrypsin Deficiency Treatment Consumption Forecast (2019-2025) 11.4 Global Alpha 1 Antitrypsin Deficiency Treatment Production, Revenue and Price Forecast by Type (2019-2025) 11.5 Global Alpha 1 Antitrypsin Deficiency Treatment Consumption Forecast by Application (2019-2025) 12 Research Findings and Conclusion 13 Methodology and Data Source 13.1 Methodology/Research Approach13.1.1 Research Programs/Design 13.1.2 Market Size Estimation 13.1.3 Market Breakdown and Data Triangulation 13.2 Data Source13.2.1 Secondary Sources 13.2.2 Primary Sources 13.3 Author List
Summary: Get latest Market Research Reports on Alpha 1 Antitrypsin Deficiency Treatment . Industry analysis & Market Report on Alpha 1 Antitrypsin Deficiency Treatment is a syndicated market report, published as Global Alpha 1 Antitrypsin Deficiency Treatment Market Research Report 2019. It is complete Research Study and Industry Analysis of Alpha 1 Antitrypsin Deficiency Treatment market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.
Last updated on 26 March, 2019