3D Cell Culture Global Market – Forecast To 2021

1 EXECUTIVE SUMMARY 25

2 INTRODUCTION 29

• 2.1 KEY TAKE AWAYS 29
• 2.2 REPORT DESCRIPTION 29
• 2.3 MARKETS COVERED 31
• 2.4 STAKEHOLDERS 33
• 2.5 RESEARCH METHODOLOGY 34
  • 2.5.1 MARKET SIZE ESTIMATION 36
  • 2.5.2 MARKET CRACKDOWN AND DATA TRIANGULATION 38
  • 2.5.3 SECONDARY SOURCES 39
  • 2.5.4 KEY DATA POINTS FROM SECONDARY SOURCES 40
  • 2.5.5 PRIMARY SOURCES 41
  • 2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 41
  • 2.5.7 ASSUMPTIONS 41

3 MARKET ANALYSIS 43

• 3.1 INTRODUCTION 43
• 3.2 MARKET SEGMENTATION 44
• 3.3 FACTORS INFLUENCING MARKET 46
  • 3.3.1 DRIVERS AND OPPORTUNITIES 47
    • 3.3.1.1 Rise in research and development investments 47
    • 3.3.1.2 Rising need for organ transplantation 47
    • 3.3.1.3 Use of 3D cell culture models as a tool against animal testing 48
    • 3.3.1.4 Use of microfluidic technology 48
    • 3.3.1.5 Increasing focus on regenerative medicine 49
  • 3.3.2 RESTRAINTS AND THREATS 50
    • 3.3.2.1 Lack of experienced and skilled professionals 50
    • 3.3.2.2 Budget restriction for small and medium sized laboratories. 50
    • 3.3.2.3 Lack of consistency in 3D cell culture products 50
    • 3.3.2.4 Stringent process controls for advanced handling capabilities 51
    • 3.3.2.5 Ethical concern over use of animal sources 51
• 3.4 REGULATORY AFFAIRS 52
  • 3.4.1 UNITED STATES 52
  • 3.4.2 EUROPE 53
  • 3.4.3 INDIA 54
  • 3.4.4 JAPAN 55
• 3.5 TECHNOLOGICAL ADVANCEMENTS 56
  • 3.5.1 INTRODUCTION 56
  • 3.5.2 ORGAN-ON-CHIP 56
  • 3.5.3 3D BIOPRINTING 57
  • 3.5.4 3D VASCULARIZED ORGANS 57
  • 3.5.5 MIMETIX 3D CELL CULTURE SCAFFOLDS 58
  • 3.5.6 NANO CULTURE PLATES 58
• 3.6 UPCOMING TECHNOLOGIES 59
• 3.7 APPROVED BIOMATERIALS 62
• 3.8 PORTER’S FIVE FORCE ANALYSIS 64
  • 3.8.1 THREAT OF NEW ENTRANTS 65
  • 3.8.2 THREAT OF SUBSTITUTES 65
  • 3.8.3 BARGAINING POWER OF SUPPLIERS 65
  • 3.8.4 BARGAINING POWER OF BUYERS 66
  • 3.8.5 RIVALRY AMONG EXISTING COMPETITORS 66
• 3.9 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 67

4 3D CELL CULTURE GLOBAL MARKET, BY TYPE 70

• 4.1 INTRODUCTION 70
• 4.2 BY TECHNOLOGY 73
  • 4.2.1 INTRODUCTION 73
  • 4.2.2 SCAFFOLD BASED PLATFORM 77
    • 4.2.2.1 Natural scaffolds 80
    • 4.2.2.1.1 Protein based biomaterials 82
    • 4.2.2.1.2 Polysaccharide based biomaterials 85
    • 4.2.2.2 Synthetic scaffolds 88
    • 4.2.2.2.1 Polymer based biomaterials 90
    • 4.2.2.2.2 Peptide based biomaterials 92
    • 4.2.2.2.3 Ceramic based biomaterials 93
    • 4.2.2.2.4 Metal based biomaterial 95
    • 4.2.2.2.4.1Aluminium 95
    • 4.2.2.3 Hybrid composite 96
  • 4.2.3 SCAFFOLD FREE PLATFORM 98
    • 4.2.3.1 Low attachment surface 102
    • 4.2.3.2 Hanging drop method 104
    • 4.2.3.3 Microfluidics 106
  • 4.2.4 BIOREACTORS 108
    • 4.2.4.1 Spinner flasks 111
    • 4.2.4.2 Rotating wall vessels (RWV) 113
    • 4.2.4.3 Perfusion bioreactors 115
  • 4.2.5 MICROCHIPS 117
  • 4.2.6 HYDROGELS 119
• 4.3 BY CONSUMABLES 121
  • 4.3.1 INTRODUCTION 121
  • 4.3.2 CELLS AND TISSUES 124
  • 4.3.3 MEDIA AND SERA 126
  • 4.3.4 MICROPLATE AND REAGENTS 129
  • 4.3.5 ASSAY KITS 132

5 3D CELL CULTURE GLOBAL MARKET, BY APPLICATIONS 134

• 5.1 INTRODUCTION 134
• 5.2 BASIC RESEARCH 137
• 5.3 TOXICITY AND DRUG SAFETY SCREENING 139
• 5.4 TISSUE ENGINEERING 141
• 5.5 STEM CELL RESEARCH 143
• 5.6 DRUG DISCOVERY 145
• 5.7 CANCER RESEARCH 147
• 5.8 GENE THERAPY 149

6 3D CELL CULTURE GLOBAL MARKET, BY END USERS 151

• 6.1 INTRODUCTION 151
• 6.2 ACADEMIC INSTITUTES 154
• 6.3 BIOTECHNOLOGY AND PHARMACEUTICAL INDUSTRIES 156
• 6.4 HOSPITALS AND DIAGNOSTIC CENTERS 158
• 6.5 OTHERS 160

7 REGIONAL ANALYSIS 162

• 7.1 INTRODUCTION 162
• 7.2 NORTH AMERICA 165
• 7.3 EUROPE 175
• 7.4 ASIA-PACIFIC 185
• 7.5 REST OF THE WORLD 195

8 COMPETITIVE LANDSCAPE 205

• 8.1 INTRODUCTION 205
• 8.2 NEW PRODUCT LAUNCHES 207
• 8.3 AGREEMENTS, PARTNERSHIP, COLLABORATION & JOINT VENTURES 215
• 8.4 EXPANSIONS, APPOVALS AND SERVICE LAUNCHES 221
• 8.5 MERGERS & ACQUISITIONS 222

9 MAJOR COMPANIES 224

• 9.1 3D BIOMATRIX 224
  • 9.1.1 OVERVIEW 224
  • 9.1.2 FINANCIALS 224
  • 9.1.3 PRODUCTS PORTFOLIO 225
  • 9.1.4 KEY DEVELOPMENTS 225
  • 9.1.5 BUSINESS STRATEGY 227
  • 9.1.6 SWOT ANALYSIS 228
• 9.2 3D BIOTEK LLC 229
  • 9.2.1 OVERVIEW 229
  • 9.2.2 FINANCIALS 229
  • 9.2.3 PRODUCT PORTFOLIO 230
  • 9.2.4 KEY DEVELOPMENTS 231
  • 9.2.5 BUSINESS STRATEGY 231
  • 9.2.6 SWOT ANALYSIS 232
• 9.3 BECTON, DICKINSON AND COMPANY 233
  • 9.3.1 OVERVIEW 233
  • 9.3.2 FINANCIALS 234
  • 9.3.3 PRODUCT PORTFOLIO 237
  • 9.3.4 KEY DEVELOPMENTS 238
  • 9.3.5 BUSINESS STRATEGY 239
  • 9.3.6 SWOT ANALYSIS 240
• 9.4 CORNING INCORPORATED 241
  • 9.4.1 OVERVIEW 241
  • 9.4.2 FINANCIALS 242
  • 9.4.3 PRODUCT PORTFOLIO 245
  • 9.4.4 KEY DEVELOPMENTS 247
  • 9.4.5 BUSINESS STRATEGY 248
  • 9.4.6 SWOT ANALYSIS 249
• 9.5 GLOBAL CELL SOLUTIONS, INC 250
  • 9.5.1 OVERVIEW 250
  • 9.5.2 FINANCIALS 250
  • 9.5.3 PRODUCT PORTFOLIO 251
  • 9.5.4 KEY DEVELOPMENTS 252
  • 9.5.5 BUSINESS STRATEGY 252
  • 9.5.6 SWOT ANALYSIS 253
• 9.6 INSPHERO AG 254
  • 9.6.1 OVERVIEW 254
  • 9.6.2 FINANCIALS 254
  • 9.6.3 PRODUCT PORTFOLIO 255
  • 9.6.4 KEY DEVELOPMENTS 256
  • 9.6.5 BUSINESS STRATEGY 259
  • 9.6.6 SWOT ANALYSIS 260
• 9.7 LONZA GROUP 261
  • 9.7.1 OVERVIEW 261
  • 9.7.2 FINANCIALS 262
  • 9.7.3 PRODUCT PORTFOLIO 265
  • 9.7.4 KEY DEVELOPMENTS 267
  • 9.7.5 BUSINESS STRATEGY 269
  • 9.7.6 SWOT ANALYSIS 270
• 9.8 NANO 3D BIOSCIENCES, INC 271
  • 9.8.1 OVERVIEW 271
  • 9.8.2 FINANCIALS 271
  • 9.8.3 PRODUCT PORTFOLIO 272
  • 9.8.4 KEY DEVELOPMENTS 273
  • 9.8.5 BUSINESS STRATEGY 274
  • 9.8.6 SWOT ANALYSIS 275
• 9.9 NANOFIBER SOLUTIONS 276
  • 9.9.1 OVERVIEW 276
  • 9.9.2 FINANCIALS 276
  • 9.9.3 PRODUCT PORTFOLIO 277
  • 9.9.4 KEY DEVELOPMENTS 278
  • 9.9.5 BUSINESS STRATEGY 278
  • 9.9.6 SWOT ANALYSIS 279
• 9.10 REPROCELL INCORPORATED 280
  • 9.10.1 OVERVIEW 280
  • 9.10.2 FINANCIALS 280
  • 9.10.3 PRODUCT PORTFOLIO 281
  • 9.10.4 KEY DEVELOPMENTS 282
  • 9.10.5 BUSINESS STRATEGY 283
  • 9.10.6 SWOT ANALYSIS 284
• 9.11 SIGMA ALDRICH CORPORATION 285
  • 9.11.1 OVERVIEW 285
  • 9.11.2 FINANCIALS 286
  • 9.11.3 PRODUCT PORTFOLIO 289
  • 9.11.4 KEY DEVELOPMENTS 290
  • 9.11.5 BUSINESS STRATEGY 292
  • 9.11.6 SWOT ANALYSIS 293
• 9.12 THERMO FISHER SCIENTIFIC, INC 294
  • 9.12.1 OVERVIEW 294
  • 9.12.2 FINANCIALS 295
  • 9.12.3 PRODUCT PORTFOLIO 298
  • 9.12.4 KEY DEVELOPMENTS 299
  • 9.12.5 BUSINESS STRATEGY 302
  • 9.12.6 SWOT ANALYSIS 303

LIST OF TABLES

TABLE 1 3D CELL CULTURE GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 28

TABLE 2 3D CELL CULTURE GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 71

TABLE 3 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 74

TABLE 4 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 75

TABLE 5 3D CELL CULTURE SCAFFOLD BASED PLATFORM GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 77

TABLE 6 3D CELL CULTURE SCAFFOLD BASED PLATFORM GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 78

TABLE 7 3D CELL CULTURE NATURAL SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 81

TABLE 8 3D CELL CULTURE SYNTHETIC SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 89

TABLE 9 3D CELL CULTURE HYBRID COMPOSITE SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 97

TABLE 10 3D CELL CULTURE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 99

TABLE 11 3D CELL CULTURE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 100

TABLE 12 LOW ATTACHMENT SURFACE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 103

TABLE 13 HANGING DROP METHOD SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 105

TABLE 14 MICROFLUIDICS SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 107

TABLE 15 3D CELL CULTURE BIORECTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 109

TABLE 16 3D CELL CULTURE BIOREACTORS GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 110

TABLE 17 3D CELL CULTURE SPINNER FLASK BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 112

TABLE 18 3D CELL CULTURE ROTATING WALL VESSEL BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 114

TABLE 19 3D CELL CULTURE PERFUSION BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 116

TABLE 20 3D CELL CULTURE MICROCHIPS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 118

TABLE 21 3D CELL CULTURE HYDROGELS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 120

TABLE 22 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 121

TABLE 23 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 122

TABLE 24 3D CELL CULTURE CELLS AND TISSUE CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 125

TABLE 25 3D CELL CULTURE MEDIA AND SERA CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 128

TABLE 26 3D CELL CULTURE MICROPLATE AND REAGENT CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 131

TABLE 27 3D CELL CULTURE ASSAY KITS CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 133

TABLE 28 3D CELL CULTURE GLOBAL MARKET REVENUE, BY APPLICATIONS, (2013-2021) ($MN) 135

TABLE 29 3D CELL CULTURE BASIC RESEARCH APPLICATION GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 138

TABLE 30 3D CELL CULTURE TOXICITY AND DRUG SAFETY SCREENING APPLICATION GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 140

TABLE 31 3D CELL CULTURE TISSUE ENGINEERING APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 142

TABLE 32 3D CELL CULTURE STEM CELL RESEARCH APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 144

TABLE 33 3D CELL CULTURE DRUG DISCOVERY APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 146

TABLE 34 3D CELL CULTURE CANCER RESEARCH APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 148

TABLE 35 3D CELL CULTURE GENE THERAPY APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 150

TABLE 36 3D CELL CULTURE GLOBAL MARKET REVENUE, BY END-USERS, (2013-2021) ($MN) 152

TABLE 37 3D CELL CULTURE ACADEMIC INSTITUTES END-USERS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 155

TABLE 38 3D CELL CULTURE BIOTECHNOLOGY AND PHARMACEUTICALS INDUSTRIES END-USERS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 157

TABLE 39 3D CELL CULTURE HOSPITALS AND DIAGNOSTIC CENTRES END-USER GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 159

TABLE 40 3D CELL CULTURE OTHER END-USERS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 161

TABLE 41 3D CELL CULTURE GLOBAL MARKET REVENUE,BY REGION, (2013-2021) ($MN) 164

TABLE 42 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 167

TABLE 43 NORTH AMERICAN 3D CELL CULTURE TECHNOLOGY MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 168

TABLE 44 NORTH AMERICAN 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 169

TABLE 45 NORTH AMERICAN 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 170

TABLE 46 NORTH AMERICAN 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 171

TABLE 47 NORTH AMERICAN 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 172

TABLE 48 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY APPLICATIONS, (2013-2021) ($MN) 173

TABLE 49 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY END-USER, (2013-2021) ($MN) 174

TABLE 50 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 177

TABLE 51 EUROPEAN 3D CELL CULTURE TECHNOLOGY MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 178

TABLE 52 EUROPEAN 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 179

TABLE 53 EUROPEAN 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 180

TABLE 54 EUROPEAN 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 181

TABLE 55 EUROPEAN 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 182

TABLE 56 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY APPLICATION, (2013-2021) ($MN) 183

TABLE 57 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY END-USER, (2013-2021) ($MN) 184

TABLE 58 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 187

TABLE 59 ASIA-PACIFIC 3D CELL CULTURE TECHNOLOGY MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 188

TABLE 60 ASIA-PACIFIC 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 189

TABLE 61 ASIA-PACIFIC 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 190

TABLE 62 ASIA-PACIFIC 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 191

TABLE 63 ASIA-PACIFIC 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 192

TABLE 64 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY APPLICATION, (2013-2021) ($MN) 193

TABLE 65 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY END USERS, (2013-2021) ($MN) 194

TABLE 66 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 197

TABLE 67 REST OF THE WORLD 3D CELL CULTURE TECHNOLOGY MARKET REVENUE BY TYPE, (2013-2021) ($MN) 198

TABLE 68 REST OF THE WORLD 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 199

TABLE 69 REST OF THE WORLD 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 200

TABLE 70 REST OF THE WORLD 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 201

TABLE 71 REST OF THE WORLD 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 202

TABLE 72 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY APPLICATION, (2013-2021) ($MN) 203

TABLE 73 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY END-USER, (2013-2021) ($MN) 204

TABLE 74 NEW PRODUCT LAUNCHES (2013-2015) 207

TABLE 75 AGREEMENTS, PARTNERSHIP, COLLABORATION & JOINT VENTURES (2013-2015) 215

TABLE 76 EXPANSIONS, APPROVALS AND SERVICE LAUNCH (2013-2015) 221

TABLE 77 MERGERS & ACQUISITIONS (2013-2015) 222

TABLE 78 BECTON, DICKINSON AND COMPANY: TOTAL REVENUE AND R&D EXPENSES (2012-2014) ($MN) 234

TABLE 79 BECTON, DICKINSON AND COMPANY: TOTAL REVENUE, BY SEGMENTS (2012-2014) ($ MN) 235

TABLE 80 BECTON, DICKINSON AND COMPANY: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($ MN) 236

TABLE 81 CORNING INCORPORATED: TOTAL REVENUE AND R&D EXPENSES (2012-2014) ($MN) 242

TABLE 82 CORNING INCORPORATED: TOTAL REVENUE, BY SEGMENTS (2012-2014) ($MN) 243

TABLE 83 CORNING INCORPORATED: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($MN) 244

TABLE 84 LONZA GROUP: TOTAL REVENUE AND R&D EXPENSES (2012-2014) ($MN) 262

TABLE 85 LONZA GROUP: TOTAL REVENUE, BY SEGMENTS (2012-2014) ($MN) 263

TABLE 86 LONZA GROUP: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($MN) 264

TABLE 87 SIGMA ALDRICH’S: TOTAL REVENUE AND R&D EXPENSES, (2012-2014) ($MN) 286

TABLE 88 SIGMA ALDRICH’S: TOTAL REVENUE, BY SEGMENTS, (2012-2014) ($MN) 287

TABLE 89 SIGMA ALDRICH’S: TOTAL REVENUE, BY GEOGRAPHY, (2012-2014) ($MN) 288

TABLE 90 THERMO FISHER SCIENTIFIC, INC: TOTAL REVENUE AND R&D EXPENSES (2012-2014) ($MN) 295

TABLE 91 THERMO FISHER SCIENTIFIC, INC : TOTAL REVENUE, BY SEGMENTS (2012-2014) ($MN) 296

TABLE 92 THERMO FISHER SCIENTIFIC, INC: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($MN) 297

LIST OF FIGURES

FIGURE 1 GLOBAL 3D CELL CULTURE MARKET SHARE AND REVENUE, BY REGION, (2013-2021) ($MN) 27

FIGURE 2 3D CELL CULTURE MARKET: RESEARCH APPROACH 35

FIGURE 3 3D CELL CULTURE MARKET: TOP-DOWN AND BOTTOM-UP APPROACH 36

FIGURE 4 3D CELL CULTURE MARKET: FORECASTING MODEL 37

FIGURE 5 3D CELL CULTURE MARKET: MARKET CRACKDOWN AND DATA TRIANGULATION 38

FIGURE 6 3D CELL CULTURE GLOBAL MARKET: MARKET SEGMENTATION 45

FIGURE 7 MARKET DYNAMICS 46

FIGURE 8 3D CELL CULTURE MARKET: PORTER’S ANALYSIS 64

FIGURE 9 3D CELL CULTURE GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2014 67

FIGURE 10 3D CELL CULTURE GLOBAL MARKET REVENUE, BY TYPE (2013-2021) ($MN) 72

FIGURE 11 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET SHARE, BY TYPE,

(2014 V’S 2021) (%) 76

FIGURE 12 SCAFFOLD BASED PLATFORMS GLOBAL MARKET SIZE, BY TYPE (2014) (%) 79

FIGURE 13 SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY TYPE, (2014) ($MN) 101

FIGURE 14 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY TYPE, (2014 V’S 2021) ($MN) 123

FIGURE 15 3D CELL CULTURE GLOBAL MARKET REVENUE, BY APPLICATION (2014) (%) 136

FIGURE 16 3D CELL CULTURE GLOBAL MARKET REVENUE, BY END-USERS (2013-2021) ($MN) 153

FIGURE 17 3D CELL CULTURE GLOBAL MARKET REVENUE, BY REGION (2013-2021) ($MN) 163

FIGURE 18 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION & END-USERS (2014 V’S 2021) ($MN) 166

FIGURE 19 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION & END-USERS (2014 V’S 2021) ($MN) 176

FIGURE 20 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION & END-USERS (2014 V’S2021) ($MN) 186

FIGURE 21 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION & END-USERS (2014 V’S 2021) ($MN) 196

FIGURE 22 KEY GROWTH STRATEGIES, (2013 – 2015) 206

FIGURE 23 SWOT: 3D BIOMATRIX 228

FIGURE 24 SWOT: 3D BIOTEK 232

FIGURE 25 SWOT: BECTON, DICKINSON AND COMPANY 240

FIGURE 26 SWOT: CORNING INCORPORATED 249

FIGURE 27 SWOT: GLOBAL CELL SOLUTIONS 253

FIGURE 28 SWOT: INSPHERO AG 260

FIGURE 29 SWOT: LONZA GROUP 270

FIGURE 30 SWOT: NANO 3D BIOSCIENCES 275

FIGURE 31 SWOT: NANOFIBER SOLUTION 279

FIGURE 32 SWOT: REPROCELL 284

FIGURE 33 SWOT: SIGMA ALDRICH 293

FIGURE 34 SWOT: THERMO FISHER SCIENTIFIC, INC 303