Spine Implants Global Market - Forecast to 2022
1 EXECUTIVE SUMMARY 33
2 INTRODUCTION 37
- 2.1 KEY TAKEAWAYS 37
- 2.2 REPORT DESCRIPTION 37
- 2.3 MARKETS COVERED 39
- 2.4 STAKEHOLDERS 41
- 2.5 RESEARCH METHODOLOGY 41
- 2.5.1 MARKET SIZE ESTIMATION 43
- 2.5.2 MARKET CRACKDOWN AND DATA TRIANGULATION 45
- 2.5.3 SECONDARY SOURCES 46
- 2.5.4 PRIMARY SOURCES 47
- 2.5.5 KEY DATA POINTS FROM SECONDARY SOURCES 47
- 2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 48
- 2.5.7 ASSUMPTIONS 48
3 MARKET ANALYSIS 50
- 3.1 INTRODUCTION 50
- 3.2 MARKET SEGMENTATION 51
- 3.3 FACTORS INFLUENCING MARKET 53
- 3.3.1 DRIVERS AND OPPORTUNTIES 54
- 3.3.1.1 Rapidly changing target population dynamics 54
- 3.3.1.2 Increasing awareness of minimally invasive surgeries 54
- 3.3.1.3 Emergence/adaptation of motion preserving (non-fusion) devices. 55
- 3.3.1.4 Robotics and anatomic specific (customizable) solutions 55
- 3.3.2 RESTRAINTS AND THREATS 56
- 3.3.2.1 High cost of treatment procedures 56
- 3.3.2.2 Cost containment measures & reimbursement issues 56
- 3.3.2.3 Lack of trained surgeons in near terms 57
- 3.3.2.4 Lack of adequate physician and patient awareness/education
about newly developed treatment procedures and technologies 57
- 3.4 REGULATORY AFFAIRS 58
- 3.4.1 U.S. 58
- 3.4.2 EUROPE 59
- 3.4.3 CHINA 60
- 3.4.4 CANADA 60
- 3.4.5 INDIA 61
- 3.4.6 JAPAN 62
- 3.5 REIMBURSEMENT SCENARIO 63
- 3.6 CPT CODES 64
- 3.7 PATENT TRENDS 66
- 3.8 TECHNOLOGICAL ADVANCEMENTS 68
- 3.8.1 ROBOTIC SPINE SURGERY 68
- 3.8.2 3D PRINTING 69
- 3.8.3 BIOMATERIALS 70
- 3.8.4 BIOCERAMIC COATING 71
- 3.8.5 SPINE NAVIGATION TECHNOLOGY 72
- 3.8.6 SPINE ALIGNMENT AID DEVICES 72
- 3.9 UPCOMING TECHNOLOGIES 73
- 3.10 CLINICAL TRIALS 75
- 3.11 PORTER’S FIVE FORCE ANALYSIS 80
- 3.11.1 THREAT OF NEW ENTRANTS 81
- 3.11.2 THREAT OF SUBSTITUTES 81
- 3.11.3 BARGAINING POWER OF SUPPLIERS 81
- 3.11.4 BARGAINING POWER OF BUYERS 82
- 3.11.5 RIVALRY AMONG EXISTING COMPETITORS 82
- 3.12 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 83
4 SPINE IMPLANTS GLOBAL MARKET, BY TYPE 87
- 4.1 INTRODUCTION 87
- 4.2 FUSION 92
- 4.2.1 INTERBODY 97
- 4.2.1.1 Cervical 102
- 4.2.1.1.1 Anterior cervical interbody fusion 105
- 4.2.1.2 Thoracic 106
- 4.2.1.2.1 Thoracolumbar interbody fusion 107
- 4.2.1.3 Lumbar 110
- 4.2.1.3.1 Anterior lumbar interbody fusion 115
- 4.2.1.3.2 Posterior lumbar interbody fusion & transforaminal lumbar
interbody fusion 118
- 4.2.1.3.3 Lateral lumbar interbody fusion (XLIF) 121
- 4.2.1.3.4 Lumbosacral interbody fusion (AXIAL LIF) 124
- 4.2.2 PLATE 127
- 4.2.2.1 Cervical 132
- 4.2.2.1.1 Anterior cervical plate fixation 137
- 4.2.2.1.2 Posterior laminoplasty fixation system 140
- 4.2.2.2 Thoracic 143
- 4.2.2.2.1 Anterior thoracolumbar plate fixation system 148
- 4.2.2.3 Lateral thoracolumbar plate system 151
- 4.2.2.4 Lumbar 154
- 4.2.2.4.1 Anterior lumbar and lumbosacral plate fixation 159
- 4.2.2.4.2 Sacral plate 162
- 4.2.3 FIXATION (SCREW & ROD) 165
- 4.2.3.1 Cervical 170
- 4.2.3.1.1 Posterior occpitocervicothoracic (POCT) fixation 173
- 4.2.3.1.2 Posterior cervicothoracic fixation system 173
- 4.2.3.2 Thoracic 174
- 4.2.3.2.1 Posterior thoracolumbar fixation system 177
- 4.2.3.3 Lumbar 178
- 4.2.3.3.1 Posterior lumbar fixation 181
- 4.2.3.3.2 Posterior lumbosacral fixation 182
- 4.2.3.3.3 Sacroiliac fixation system 183
- 4.2.3.4 Others 184
- 4.2.3.4.1 Pedicle screw 187
- 4.2.3.4.2 Deformity correction - posterior spine fixation system 188
- 4.2.4 VERTEBRAL BODY REPLACEMENT (VBR) 189
- 4.2.5 SPINOUS PROCESS FIXATION DEVICE 190
- 4.2.6 BONE STAPLE 190
- 4.2.7 CROSS CONNECTORS / TRANSVERSE CONNECTORS 191
- 4.2.8 ROD AND BAND FIXATION SYSTEM 191
- 4.3 NON FUSION 192
- 4.3.1 DYNAMIC STABILIZATION 197
- 4.3.1.1 Interspinous process spacers 202
- 4.3.1.2 Pedicle screw based systems 205
- 4.3.1.3 Facet arthroplasty system 208
- 4.3.2 ARTIFICIAL DISCS 211
- 4.3.2.1 Cervical artificial disc 216
- 4.3.2.2 Lumbar artificial disc 219
- 4.3.3 NUCLEUS REPLACEMENT 222
- 4.3.4 ANNULUS REPAIR DEVICES 225
- 4.3.1 DYNAMIC STABILIZATION 197
- 4.4 VERTEBRAL COMPRESSION FRACTURE TREATMENT DEVICES 228
- 4.4.1 VERTEBROPLASTY 233
- 4.4.2 KYPHOPLASTY 236
- 4.5 BIOLOGICS 239
- 4.5.1 SPINAL BONE GRAFT 244
- 4.5.2 SPINAL BONE GRAFT SUBSTITUTE 247
- 4.5.2.1 Synthetic bone graft 250
- 4.5.2.2 Demineralised bone matrix 250
- 4.5.2.3 Bone morphogenetic proteins (BMP) 251
- 4.5.2.4 Morsels and putty 252
- 4.5.3 Spine stimulators 253
5 SPINE IMPLANTS GLOBAL MARKET, BY SURGERY TYPE 256
- 5.1 INTRODUCTION 256
- 5.2 OPEN SURGERY 261
- 5.3 MINIMALLY INVASIVE SURGERY (MIS) 264
- 5.3.1 ROBOTIC SURGERY 265
6 SPINE IMPLANTS GLOBAL MARKET, BY PROCEDURE 268
- 6.1 INTRODUCTION 268
- 6.2 DISCECTOMY 273
- 6.3 FORAMINOTOMY/FORAMINECTOMY 276
- 6.4 LAMINOTOMY/LAMINECTOMY 279
- 6.5 FACETECTOMY 282
- 6.6 CORPECTOMY 285
- 6.7 SACRO-ILICAC JOINT TREATMENT 288
7 SPINE IMPLANTS GLOBAL MARKET BY END-USERS 289
- 7.1 INTRODUCTION 289
- 7.2 HOSPITALS 294
- 7.3 PRIVATE SPINE CLINICS 298
8 REGIONAL ANALYSIS 301
- 8.1 INTRODUCTION 301
- 8.2 NORTH AMERICA 304
- 8.3 EUROPE 328
- 8.4 ASIA-PACIFIC 352
- 8.5 ROW 376
9 COMPANY DEVELOPMENTS 399
- 9.1 INTRODUCTION 399
- 9.2 NEW PRODUCT LAUNCHES 401
- 9.3 APPROVALS 410
- 9.4 MERGERS & ACQUISITIONS 416
- 9.5 AGREEMENTS & COLLOBORATIONS 419
10 MAJOR COMPANIES 421
- 10.1 ALPHATEC SPINE, INC. 421
- 10.1.1 OVERVIEW 421
- 10.1.2 FINANCIALS 422
- 10.1.3 PRODUCT PORTFOLIO 424
- 10.1.4 KEY DEVELOPMENTS 426
- 10.1.5 BUSINESS STRATEGY 428
- 10.1.6 SWOT ANALYSIS 429
- 10.2 B.BRAUN MELSUNGEN AG 430
- 10.2.1 OVERVIEW 430
- 10.2.2 FINANCIALS 431
- 10.2.3 PRODUCT PORTFOLIO 434
- 10.2.4 KEY DEVELOPMENTS 436
- 10.2.5 BUSINESS STRATEGY 436
- 10.2.6 SWOT ANALYSIS 437
- 10.3 DEPUY SYNTHES (JOHNSON & JOHNSON) 438
- 10.3.1 OVERVIEW 438
- 10.3.2 FINANCIALS 439
- 10.3.3 PRODUCT PORTFOLIO 444
- 10.3.4 KEY DEVELOPMENTS 447
- 10.3.5 BUSINESS STRATEGY 448
- 10.3.6 SWOT ANALYSIS 449
- 10.4 EXACTECH, INC 450
- 10.4.1 OVERVIEW 450
- 10.4.2 FINANCIALS 451
- 10.4.3 PRODUCT PORTFOLIO 454
- 10.4.4 KEY DEVELOPMENTS 455
- 10.4.5 BUSINESS STRATEGY 455
- 10.4.6 SWOT ANALYSIS 456
- 10.5 GLOBUS MEDICAL, INC. 457
- 10.5.1 OVERVIEW 457
- 10.5.2 FINANCIALS 458
- 10.5.3 PRODUCT PORTFOLIO 461
- 10.5.4 KEY DEVELOPMENTS 465
- 10.5.5 BUSINESS STRATEGY 467
- 10.5.6 SWOT ANALYSIS 468
- 10.6 K2M GROUP HOLDINGS, INC 469
- 10.6.1 OVERVIEW 469
- 10.6.2 FINANCIALS 470
- 10.6.3 PRODUCT PORTFOLIO 473
- 10.6.4 KEY DEVELOPMENTS 476
- 10.6.5 BUSINESS STRATEGY 480
- 10.6.6 SWOT ANALYSIS 481
- 10.7 LDR HOLDING CORPORATION 482
- 10.7.1 OVERVIEW 482
- 10.7.2 FINANCIALS 483
- 10.7.3 PRODUCT PORTFOLIO 486
- 10.7.4 KEY DEVELOPMENTS 487
- 10.7.5 BUSINESS STRATEGY 488
- 10.7.6 SWOT ANALYSIS 489
- 10.8 MEDTRONIC, PLC 490
- 10.8.1 OVERVIEW 490
- 10.8.2 FINANCIALS 491
- 10.8.3 PRODUCT PORTFOLIO 495
- 10.8.4 KEY DEVELOPMENTS 496
- 10.8.5 BUSINESS STRATEGY 500
- 10.8.6 SWOT ANALYSIS 501
- 10.9 NUVASIVE, INC. 502
- 10.9.1 OVERVIEW 502
- 10.9.2 FINANCIALS 503
- 10.9.3 PRODUCT PORTFOLIO 506
- 10.9.4 KEY DEVELOPMENTS 507
- 10.9.5 BUSINESS STRATEGY 509
- 10.9.6 SWOT ANALYSIS 510
- 10.10 ORTHOFIX INTERNATIONAL N.V 511
- 10.10.1 OVERVIEW 511
- 10.10.2 FINANCIALS 512
- 10.10.3 PRODUCT PORTFOLIO 514
- 10.10.4 KEY DEVELOPMENTS 517
- 10.10.5 BUSINESS STRATEGY 517
- 10.10.6 SWOT ANALYSIS 518
- 10.11 STRYKER CORPORATION 519
- 10.11.1 OVERVIEW 519
- 10.11.2 FINANCIALS 520
- 10.11.3 PRODUCT PORTFOLIO 524
- 10.11.4 PRODUCT PORTFOLIO 526
- 10.11.5 BUSINESS STRATEGY 527
- 10.11.6 SWOT ANALYSIS 528
- 10.12 ZIMMER BIOMET HOLDINGS, INC 528
- 10.12.1 OVERVIEW 529
- 10.12.2 FINANCIALS 529
- 10.12.3 PRODUCT PORTFOLIO 533
- 10.12.4 KEY DEVELOPMENTS 535
- 10.12.5 BUSINESS STRATEGY 536
- 4.2.1 INTERBODY 97
- 3.3.1 DRIVERS AND OPPORTUNTIES 54
The spine devices global market is expected to grow at a CAGR of around XX% from 2015 to 2022. The spine column or vertebral column is made of a series of 33 individual bones that interlock with each other to form the spine column. These vertebrae are divided into 5 regions termed cervical, thoracic, lumbar, sacrum, and coccyx. The spine is an important structure in the body which performs functions such as weight bearing and protection of the spinal cord. Increase in ageing population and lifestyle diseases, awareness of minimally invasive surgeries, the emergence of motion preserving (non-fusion) devices and availability of robotic and customised or patient specific solutions are driving the market growth.
While, high cost for the spine procedures that includes device & technology cost, hospital cost, post operative cost, pharmaceuticals, physician cost and lack of reimbursement negatively influence market expansion. The technological advancements in spine surgery requires surgeons to continuously train and improve skills that involves high costs before becoming a qualified practitioner, resulting in shortage of skilled spine surgeons. These factors are hindering market growth.
The Spine Implants global market is segmented based on the product type into fusion and non-fusion products. Further, based on the type of surgical procedure into open and minimally invasive, based on the type of procedure into discectomy, foraminectomy/ foraminotomy, laminectomy/laminotomy, facetectomy and corpectomy. Based on end-users into hospitals and private clinics and based on different geographical regions.
North America accounts for the highest market share followed by Asia-Pacific. The steep rise in ageing population, increase in minimally invasive surgeries and favourable government policies makes U.S. the leader of the Spine Implants global market. However, Asian countries especially Japan and China’s are the fast growing regions with its growing demand for Spine Implants.
Major players in the Spine Implants global market includes DePuy Synthes (U.S.), Medtronic (Ireland), B Braun (Aesculap) (Germany), Alphatec spine(U.S.), Exactech(U.S.), K2M, Inc, LDR Holdings (U.S.), NuVasive (U.S.), Stryker (U.S.), Orthofix International (U.S.) and Zimmer-Biomet (U.S.).
The report provides an in depth market analysis of the above mentioned segments across the following regions:
• North America
• Europe
• Asia-Pacific
• Rest of the World (RoW)