1 EXECUTIVE SUMMARY 33

2 INTRODUCTION 38

• 2.1 KEY TAKE AWAYS 38
• 2.2 REPORT DESCRIPTION 39
• 2.3 MARKETS COVERED 42
• 2.4 STAKEHOLDERS 44
• 2.5 RESEARCH METHODOLOGY 44
  • 2.5.1 MARKET SIZE ESTIMATION 46
  • 2.5.2 MARKET BREAKDOWN AND DATA TRIANGULATION 48
  • 2.5.3 SECONDARY SOURCES 49
  • 2.5.4 PRIMARY SOURCES 49
  • 2.5.5 KEY DATA POINTS FROM SECONDARY SOURCES 50
  • 2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 51
  • 2.5.7 ASSUMPTIONS 51

3 MARKET ANALYSIS 53

• 3.1 INTRODUCTION 53
• 3.2 MARKET SEGMENTATION 54
• 3.3 FACTORS INFLUENCING MARKET 56
  • 3.3.1 DRIVERS AND OPPORTUNITIES 57
    • 3.3.1.1 Rapid rise in biologics 57
    • 3.3.1.2 Growing importance of chromatography tests in drug approvals 57
    • 3.3.1.3 New international cgmp and cgdp certification for pharmaceutical excipients 58
    • 3.3.1.4 Technological advancements in chromatography instruments & reagents 59
    • 3.3.1.5 Increasing life sciences r&d spending 60
    • 3.3.1.6 Growing food safety concerns 61
    • 3.3.1.7 Increased use of chromatography in diverse applications 62
    • 3.3.1.8 Expanding emerging markets 63
  • 3.3.2 RESTRAINTS AND THREATS 63
    • 3.3.2.1 High unit and maintenance cost of advanced equipments. 63
    • 3.3.2.2 Mature product segment and pricing pressure 64
    • 3.3.2.3 Stringent regulations 65
• 3.4 PORTER’S FIVE FORCE ANALYSIS 66
  • 3.4.1 THREAT OF NEW ENTRANTS 67
  • 3.4.2 THREAT OF SUBSTITUTES 67
  • 3.4.3 RIVALRY AMONG EXISTING COMPETITORS 68
  • 3.4.4 BARGAINING POWER OF SUPPLIERS 68
  • 3.4.5 BARGAINING POWER OF BUYERS 68
• 3.5 REGULATORY AFFAIRS 69
  • 3.5.1 NORTH AMERICA 70
  • 3.5.2 EUROPE 72
  • 3.5.3 CHINA 73
  • 3.5.4 JAPAN 74
  • 3.5.5 INDIA 74
• 3.6 MARKET SHARE ANALYSIS 76
  • 3.6.1 MARKET SHARE ANALYSIS OF CHROMATOGRAPHY GLOBAL MARKET 76
  • 3.6.2 MARKET SHARE ANALYSIS OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) GLOBAL MARKET 78
  • 3.6.3 MARKET SHARE ANALYSIS OF LC-MS GLOBAL MARKET 80
  • 3.6.4 MARKET SHARE ANALYSIS OF GAS CHROMATOGRAPHY (GC) GLOBAL MARKET 82
  • 3.6.5 MARKET SHARE ANALYSIS OF GAS CHROMATOGRAPHY MASS SPECTROMETRY (GC-MS) GLOBAL MARKET 84
• 3.7 NEW PRODUCT LAUNCHES IN CHROMATOGRAPHY MARKET 85
• 3.8 TECHNOLOGICAL ADVANCEMENTS 90
  • 3.8.1 ADVANCEMENTS IN INSTRUMENTS 90
  • 3.8.2 ADVANCEMENTS IN CONSUMABLES 91
• 3.9 SUPPLY CHAIN ANALYSIS 92
• 3.10 REFURBISHED DEVICES 95

4 CHROMATOGRAPHY GLOBAL MARKET, BY PROCESS TYPE 97

• 4.1 INTRODUCTION 97
• 4.2 PREPARATIVE CHROMATOGRAPHY 98
• 4.3 PROCESS (ANALYTICAL) CHROMATOGRAPHY 102

5 CHROMATOGRAPHY GLOBAL MARKET, BY TECHNOLOGY 104

• 5.1 INTRODUCTION 104
• 5.2 LIQUID CHROMATOGRAPHY 106
  • 5.2.1 HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) 112
    • 5.2.1.1 Ultra-high pressure liquid chromatography (UHPLC) 113
    • 5.2.1.2 Reverse-phase chromatography 114
    • 5.2.1.3 Normal-phase chromatography 114
    • 5.2.1.4 Affinity chromatography 115
    • 5.2.1.5 Chiral chromatography 115
    • 5.2.1.6 Adsorption chromatography 115
    • 5.2.1.7 Multimodal chromatography 116
    • 5.2.1.8 Ion chromatography (Ion-exchange chromatography) 116
    • 5.2.1.9 Hydrophilic and hydrophobic interaction chromatography 116
  • 5.2.2 LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (LC-MS) 118
  • 5.2.3 OTHERS 121
• 5.3 THIN LAYER CHROMATOGRAPHY (TLC) 125
• 5.4 GAS CHROMATOGRAPHY (GC) 128
• 5.5 SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC) 131

6 CHROMATOGRAPHY GLOBAL MARKET, BY PRODUCTS 135

• 6.1 INTRODUCTION 135
• 6.2 INSTRUMENTS 136
  • 6.2.1 SYSTEMS 141
  • 6.2.2 DETECTORS 142
    • 6.2.2.1 Liquid chromatography detectors 146
    • 6.2.2.1.1 UV visible detectors 149
    • 6.2.2.1.2 Refractive index detectors 151
    • 6.2.2.1.3 Fluorescence detectors 152
    • 6.2.2.1.4 Mass liquid chromatography detectors 154
    • 6.2.2.1.5 Other liquid chromatography detectors 155
    • 6.2.2.2 Gas chromatography detectors 156
    • 6.2.2.2.1 Flame ionization detectors (FID) 159
    • 6.2.2.2.2 Mass gc detectors 161
    • 6.2.2.2.3 Thermal conductivity detector (tcd) 162
    • 6.2.2.2.4 Other gas chromatography detectors 164
    • 6.2.2.3 SFC detectors 165
  • 6.2.3 PUMPS 166
  • 6.2.4 OTHER INSTRUMENTS 170
• 6.3 CONSUMABLES 173
  • 6.3.1 COLUMNS 176
    • 6.3.1.1 Columns by technology 180
    • 6.3.1.1.1 Liquid chromatography columns 180
    • 6.3.1.1.2 Gas chromatography columns 195
    • 6.3.1.1.3 SFC columns 197
    • 6.3.1.2 Columns by packing type 199
    • 6.3.1.2.1 Pre-packed columns 202
    • 6.3.1.2.2 Empty columns 204
    • 6.3.2 REAGENTS 207
      • 6.3.2.1 Solvents 210
      • 6.3.2.2 Buffers 213
      • 6.3.2.3 Derivatization reagent 215
      • 6.3.2.4 Ion-pair reagents 218
    • 6.3.3 RESINS 221
      • 6.3.3.1 Ion exchange (IEX) chromatography resins 225
      • 6.3.3.2 Affinity chromatography resins 228
      • 6.3.3.2.1 Protein A affinity resins 232
      • 6.3.3.2.2 Protein G affinity resins 234
      • 6.3.3.2.3 Protein L affinity resins 235
      • 6.3.3.2.4 Imobilized metal affinity chromatography (IMAC) resins 236
      • 6.3.3.2.5 Others 237
      • 6.3.3.3 Hydrophobic interaction chromatography (HIC) resins 239
      • 6.3.3.4 Size exclusion chromatography (SFC) resins 241
      • 6.3.3.5 Multimodal chromatography resins 243
    • 6.3.4 OTHER CONSUMBALES 245
  • 6.4 SOFTWARE AND SERVICES 248

  7 CHROMATOGRAPHY GLOBAL MARKET, BY APPLICATION 251

  • 7.1 INTRODUCTION 251
  • 7.2 PHARMA AND BIOTECH INDUSTRY 253
  • 7.3 FOOD AND BEVERAGE INDUSTRY 257
  • 7.4 ENVIRONMENTAL APPLICATION 260
  • 7.5 AGRICULTURE AND CHEMICAL INDUSTRY 262
  • 7.6 OIL AND PETROLEUM INDUSTRY 265
  • 7.7 OTHERS (COSMETICS, FORENSIC TOXICOLOGY) 267

  8 REGIONAL MARKET ANALYSIS 270

  • 8.1 INTRODUCTION 270
  • 8.2 NORTH AMERICA 272
    • 8.2.1 U.S. 296
    • 8.2.2 OTHERS 300
  • 8.3 EUROPE 304
    • 8.3.1 GERMANY 329
    • 8.3.2 FRANCE 334
    • 8.3.3 U.K. 337
    • 8.3.4 OTHERS 341
  • 8.4 ASIA 346
    • 8.4.1 CHINA 369
    • 8.4.2 JAPAN 375
    • 8.4.3 INDIA 379
    • 8.4.4 OTHERS 383
  • 8.5 REST OF THE WORLD (ROW) 388
    • 8.5.1 BRAZIL 411
    • 8.5.2 REST OF LATIN AMERICA 415
    • 8.5.3 MIDDLE EAST AND OTHER COUNTRIES 419

  9 COMPETITIVE LANDSCAPE 424

  • 9.1 INTRODUCTION 424
  • 9.2 NEW PRODUCT LAUNCHES 425
  • 9.3 AGREEMENTS, PARTNERSHIP, COLLABORATION & JOINT VENTURES 441
  • 9.4 APPROVALS 443
  • 9.5 MERGERS & ACQUISITIONS 444
  • 9.6 OTHER DEVELOPMENTS 446

  10 MAJOR COMPANIES 449

  • 10.1 AGILENT TECHNOLOGIES 449
    • 10.1.1 OVERVIEW 449
    • 10.1.2 FINANCIALS 450
    • 10.1.3 PRODUCT PORTFOLIO 452
    • 10.1.4 KEY DEVELOPMENTS 472
    • 10.1.5 BUSINESS STRATEGY 474
    • 10.1.6 SWOT ANALYSIS 475
  • 10.2 BIO-RAD LABORATORIES 476
    • 10.2.1 OVERVIEW 476
    • 10.2.2 FINANCIALS 477
    • 10.2.3 PRODUCT PORTFOLIO 479
    • 10.2.4 KEY DEVELOPMENTS 491
    • 10.2.5 BUSINESS STRATEGY 491
    • 10.2.6 SWOT ANALYSIS 492
  • 10.3 BRUKER CORPORATION 493
    • 10.3.1 OVERVIEW 493
    • 10.3.2 FINANCIALS 494
    • 10.3.3 PRODUCT PORTFOLIO 496
    • 10.3.4 KEY DEVELOPMENTS 497
    • 10.3.5 BUSINESS STRATEGY 503
    • 10.3.6 SWOT ANALYSIS 504
  • 10.4 DANAHER CORPORATION 505
    • 10.4.1 OVERVIEW 505
    • 10.4.2 FINANCIALS 506
    • 10.4.3 PRODUCT PORTFOLIO 508
    • 10.4.4 KEY DEVELOPMENTS 519
    • 10.4.5 BUSINESS STRATEGY 524
    • 10.4.6 SWOT ANALYSIS 525
  • 10.5 GE (GENERAL ELECTRIC COMPANY) 526
    • 10.5.1 OVERVIEW 526
    • 10.5.2 FINANCIALS 527
    • 10.5.3 PRODUCT PORTFOLIO 530
    • 10.5.4 KEY DEVELOPMENTS 532
    • 10.5.5 BUSINESS STRATEGY 534
    • 10.5.6 SWOT ANALYSIS 535
  • 10.6 MERCK KGAA 536
    • 10.6.1 OVERVIEW 536
    • 10.6.2 FINANCIALS 537
    • 10.6.3 PRODUCT PORTFOLIO 540
    • 10.6.4 KEY DEVELOPMENTS 542
    • 10.6.5 BUSINESS STRATEGY 544
    • 10.6.6 SWOT ANALYSIS 545
  • 10.7 PERKINELMER, INC. 546
    • 10.7.1 OVERVIEW 546
    • 10.7.2 FINANCIALS 547
    • 10.7.3 PRODUCT PORTFOLIO 549
    • 10.7.4 KEY DEVELOPMENTS 551
    • 10.7.5 BUSINESS STRATEGY 552
    • 10.7.6 SWOT ANALYSIS 554
  • 10.8 SHIMADZU CORPORATION 555
    • 10.8.1 OVERVIEW 555
    • 10.8.2 FINANCIALS 556
    • 10.8.3 PRODUCT PORTFOLIO 558
    • 10.8.4 KEY DEVELOPMENTS 562
    • 10.8.5 BUSINESS STRATEGY 568
    • 10.8.6 SWOT ANALYSIS 569
  • 10.9 THERMO FISHER SCIENTIFIC 570
    • 10.9.1 OVERVIEW 570
    • 10.9.2 FINANCIALS 571
    • 10.9.3 PRODUCT PORTFOLIO 573
    • 10.9.4 KEY DEVELOPMENTS 580
    • 10.9.5 BUSINESS STRATEGY 583
    • 10.9.6 SWOT ANALYSIS 584
  • 10.10 WATERS CORPORATION 585
    • 10.10.1 OVERVIEW 585
    • 10.10.2 FINANCIALS 586
    • 10.10.3 PRODUCT PORTFOLIO 589
    • 10.10.4 KEY DEVELOPMENTS 594
    • 10.10.5 BUSINESS STRATEGY 598

Chromatography is the one of the various separation techniques of analytical chemistry for the qualitative and quantitative separation of the sample mixture like biological or chemical compounds. The basic principle of the technique is that solute gets distributed between two phases- mobile phase and a stationary phase. The major technologies of this technique are Liquid Chromatography (LC), Gas Chromatography (GC), Supercritical Fluid Chromatography (SFC) and Thin Layer Chromatography. Chromatography has numerous applications across industries with major share in Pharma & Biotech industries. It is extensively used in biochemical research for the separation and detection of compounds of biological origin.
The global Chromatography market is poised to grow at a mid single digit CAGR to reach $18,077.7 million by 2024. Chromatography market is mainly classified by Process type, Technology, Products and applications. The Chromatography global market is broadly classified as Preparative Chromatography and Process Chromatography based on Process type. Among preparative and process chromatography type, process chromatography occupied the major share in 2017 and is expected to grow at strong CAGR. Based on Technology, the market is classified into Liquid Chromatography (LC), Gas Chromatography, Supercritical Fluid Chromatography (SFC) and Thin Layer Chromatography (TLC). Among technology, liquid chromatography occupied the major share in 2017 and is expected to grow at a mid single digit CAGR. Liquid Chromatography market is further divide into High Performance Liquid Chromatography (HPLC), LC-MS and Other liquid chromatography technology. Among liquid chromatography global market, High Performance Liquid Chromatography (HPLC) market held the major share and LC-MS market is expected to grow at a highest CAGR.
Chromatography market is segmented on the basis of Products as Instruments, Consumables and Software & Services. Among chromatography products, consumables occupied the major share in 2017. Chromatography Instruments global market is further segmented into Systems, Detectors, Pumps and other instruments. Among Instrument segment, chromatography systems commanded the major share of revenue. Detectors market is further classified into Liquid Chromatography (LC) detectors, Gas Chromatography (GC) detectors and SFC detectors.
Chromatography Consumables market is divided into Reagents, resins, columns and other consumables. Among chromatography consumables, regents occupied the major share of in 2017 and are expected to grow at a high single digit CAGR. Chromatography reagents market is further classified into Solvents, buffers, Derivatization Reagents and Ion-Pair reagents. Chromatography resins market is further segmented into Ion-exchange chromatography resins, Affinity chromatography resins, Hydrophobic Interaction chromatography (HIC) resins, Size Exclusion chromatography (SFC) resins and multimodal chromatography resins. Among chromatography resins, affinity chromatography resins held the maximum share in 2017.
Based on Technology, chromatography columns market is further divided into Liquid Chromatography (LC) columns, Gas Chromatography (GC) columns and SFC columns. LC columns occupied the major share of 62.5% in 2017 and are expected to grow at a strong CAGR. Based on packing type chromatography columns market is also segmented into pre-packed columns and empty columns. Among Chromatography Columns, by packing type, pre-packed columns held the major share in 2017.
Chromatography market application segment is classified into Pharma & Biotech Industries, environmental applications, food & beverage Industries, agricultural & chemical Industries, oil and petroleum industries and other applications. Among Chromatography applications, Pharma & Biotech Industries held the maximum share in 2017 and is expected to grow at a mid single digit CAGR.
Geographically, North America accounts for the highest market share followed by Asia-Pacific. The Asian countries especially China and India are the fastest growing regions. Asia-Pacific is projected to grow with a highest CAGR from 2017 to 2024.
Major players in Chromatography global market include Agilent Technologies Inc., (U.S.), Bio-Rad Laboratories (U.S.), Bruker Corporation (U.S.), Danaher Corporation (U.S.), GE Healthcare (U.S.), Merck KGaA (Germany), PerkinElmer Inc., (U.S.), Shimadzu Corporation (Japan), ThermoFisher Scientific (U.S.) and Waters Corporation (U.S.)
The report provides an in depth market analysis of the above mentioned segments across the following regions:
• North America
• Europe
• Asia-Pacific
• Rest of the World